HOME HELP FEEDBACK SUBSCRIPTIONS ALL ISSUES SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Katz, I. R. Articles by Kallan, M. J. Search for Related Content PubMed PubMed Citation Articles by Katz, I. R. Articles by Kallan, M. J.

Validating the Diagnosis of Delirium and Evaluating its Association With Deterioration Over a One-Year Period

Received February 2, 2000; revised June 2, 2000; accepted July 20, 2000. From the Section on Geriatric Psychiatry, University of Pennsylvania. Address correspondence to Dr. Katz, Section on Geriatric Psychiatry, University of Pennsylvania, 3600 Market Street, Room 758, Philadelphia, PA 19104.

The authors probed the associations between clinical diagnoses and independent research measures of cognitive, behavioral, and electroencephalographic (EEG) changes in hospitalized older patients and investigated the contribution of medical illness to deterioration. Patients (N=96; 47 of whom were hospitalized during the course of 1 year; 12 diagnosed with delirium) received tests of cognitive and physical functioning and the Cumulative Illness Rating Scale, specific neuropsychological tests, and a two-channel EEG. Delirium was associated with independent measures of cognitive decline and EEG slowing. Hospitalization was associated with deterioration in functional status during the year, whether or not patients showed delirium. Results suggest that medical illness leading to hospitalization can contribute significantly to deterioration in self-care, and, when it is associated with delirium, to deterioration in cognitive performance and cerebral activity over a period of 1 year.

Key Words: Delirium • Syndromes Secondary to General Medical Disorders • Longitudinal Studies

This article has been cited by other articles:

				R. O. Hopkins, L. K. Weaver, D. Collingridge, R. B. Parkinson, K. J. Chan, and J. F. Orme Jr. Two-Year Cognitive, Emotional, and Quality-of-Life Outcomes in Acute Respiratory Distress Syndrome Am. J. Respir. Crit. Care Med., February 15, 2005; 171(4): 340 - 347. [Abstract] [Full Text] [PDF]

				R. Mistry, I. Gokhman, R. Bastani, R. Gould, E. Jimenez, A. Maxwell, C. McDermott, J. Rosansky, W. Van Stone, L. Jarvik, et al. Measuring Medical Burden Using CIRS in Older Veterans Enrolled in UPBEAT, a Psychogeriatric Treatment Program: A Pilot Study J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2004; 59(10): M1068 - M1075. [Abstract] [Full Text] [PDF]

				I. R. Katz, K. J. Curyto, T. TenHave, J. Mossey, L. Sands, and M. J. Kallan Validating the Diagnosis of Delirium and Evaluating Its Association With Deterioration Over a One-Year Period Focus, April 1, 2004; 2(2): 314 - 323. [Abstract] [Full Text] [PDF]

				E. W. Ely, S. K. Inouye, G. R. Bernard, S. Gordon, J. Francis, L. May, B. Truman, T. Speroff, S. Gautam, R. Margolin, et al. Delirium in Mechanically Ventilated Patients: Validity and Reliability of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) JAMA, December 5, 2001; 286(21): 2703 - 2710. [Abstract] [Full Text] [PDF]