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Am J Geriatr Psychiatry 9:67-71, February 2001
© 2001 American Association for Geriatric Psychiatry


Regular Article

Personality Disorder Symptoms Predict Declines in Global Functioning and Quality of Life in Elderly Depressed Patients

Robert C. Abrams, M.D., George S. Alexopoulos, M.D., Lisa A. Spielman, Ph.D., Ellen Klausner, Ph.D., and Tatsuyuki Kakuma, Ph.D.

Received September 17, 1999; revised March 9, 2000; accepted April 12, 2000. From The New York Hospital-Cornell Medical Center, New York, NY. Address correspondence to Dr. Abrams, The New York Hospital-Cornell Medical Center Payne Whitney Clinic, Box 140, 525 E. 68th St., New York, NY 10021. e-mail: rabrams{at}med.cornell.edu

The authors evaluated personality disorder symptoms as predictors of change in global functioning and quality of life among elderly depressed patients. Treated elderly patients (N=40) who no longer met RDC criteria for major depression were assessed for personality disorders, depression, global functioning, and quality of life after treatment of the acute episode and at 1-year follow-up. In interaction with persisting or recurrent depression, Cluster B personality disorder symptoms contributed to declines in global functioning and quality of life over a 1-year period. Personality disorder symptoms in elderly patients appear to operate as co-factors that amplify or exacerbate the impact of residual depression on long-term functioning and quality of life.

Key Words: Depression • Personality Disorder • Comorbidity




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