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Regular Article |
Received May 21, 1997; revised October 26, 1997; accepted June 4, 1998. From The New York Hospital-Cornell Medical Center, Westchester Division, White Plains, New York, and Cornell Institute of Geriatric Psychiatry. Address correspondence to Dr. Young, New York Hospital-Cornell Medical Center, Westchester Division, 21 Bloomingdale Road, White Plains, NY 10605.
In geriatric patients with major depression (N=15), the authors compared response to treatment with nortriptyline as it relates to brain morphology assessed by computed tomography. There was a significant negative association between ventriclebrain ratio and response to nortriptyline (rs=0.63; P=0.015).
Key Words: Depression Nortriptyline Neuroanatomy
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