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Late-Life Onset of Psychotic Symptoms

Received August 21, 1996; revised January 8, 1997; accepted November 17, 1997. From the Department of Psychiatry, St. Louis University School of Medicine, St. Louis, MO. Address correspondence to Dr. Grossberg, Department of Psychiatry, St. Louis University School of Medicine, 1221 South Grand, St. Louis, MO 63104.

The authors retrospectively evaluated the etiology and clinical findings of patients with first manifestations of psychotic symptoms after the age of 65. Nearly 10% of over 1,700 consecutive geriatric patients admitted to an acute inpatient psychogeriatric unit had late-life onset psychotic symptoms. About three-fourths of these were women, usually in their seventies. Dementia of the Alzheimer's type was the most common cause of psychosis arising in late life, followed by major depression, medical/toxic causes, delirium, bipolar disorder, delusional disorder, schizophrenia, and schizoaffective disorder. Clinical manifestations consisted mostly of delusions and hallucinations.

Key Words: Psychosis • Late-Life • Age At Onset

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