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Am J Geriatr Psychiatry 6:S49-S55, May 1998
© 1998 American Association for Geriatric Psychiatry


Supplement

Cholinergic Deficiency in Alzheimer's Disease

Pathogenic Model

Lon S. Schneider, M.D.

The following is a brief review of genetic and risk factors of the neuropathology, role of oxidative and inflammatory processes, patterns of involvement and spread, relationship of apolipoprotein E4 genotype with cholinergic function, and symptom expression in Alzheimer's disease.

Key Words: Alzheimer's Disease • Cholinergic • Pathology




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I. Spoletini, C. Marra, F. Di Iulio, W. Gianni, G. Sancesario, F. Giubilei, A. Trequattrini, P. Bria, C. Caltagirone, and G. Spalletta
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Copyright © 1998 American Association for Geriatric Psychiatry