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Am J Geriatr Psychiatry 2:244-246, August 1994
© 1994 American Association for Geriatric Psychiatry
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CLINICAL AND RESEARCH REPORT

Accelerated Antidepressant Response in Geriatric Inpatients

Robert E. McCue, M.D., and Jeffrey Aronowitz, M.D.

Department of Psychiatry, Beth Israel Medical Center, New York, NY 10003.

Six elderly depressed inpatients were treated for 2 weeks with low doses of nortriptyline and fluoxeline in combination. All patients showed significant reductions in depressive symptoms with minimal side effects. Clinical improvement appeared unrelated to whether plasma levels of nortriptyline were therapeutic. The implications of this regimen for accelerated antidepressant response as well as the limitations of this report are discussed.






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Copyright © 1994 American Association for Geriatric Psychiatry