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Executive Function and Capacity to Consent to a Noninvasive Research Protocol

From the Department of Psychiatry (JES, DR, DRR), The University of Texas Health Science Center at San Antonio; the Department of Psychiatry (KGJ), Wilford Hall Medical Center, U.S. Air Force; and the South Texas Veterans Health System, Audie L. Murphy Division (GRECC) (DRR).

Objective: This study measured the association between executive function and decision-making capacity in subjects consenting to a noninvasive research protocol.

Method: Subjects consenting to a noninvasive research protocol (N = 21; mean age: 65.5 [standard deviation: 9.2] years) were administered a modified version of The MacArthur Competency Assessment Tool–Treatment (MacCAT-T), Executive Interview (EXIT25), Executive Clock Drawing Task (CLOX), and Mini-Mental State Examination (MMSE).

Results: The EXIT25 was the only instrument to correlate with each decision-making capacity domain: understanding, appreciation, and reasoning.

Conclusions: Executive function as measured by the EXIT25 is associated with multiple decision-making capacity domains.

Key Words: Decision-making capacity • competency • executive function • cognition

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