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Personality and the Association of Pain and Depression

From the Department of Clinical Psychology, The George Washington University, Washington, DC (SKC); and Program in Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY (JML, SS, PRD).

Objectives: The objectives of this study were to test the hypotheses that pain is associated with depression independent of personality and that neuroticism moderates this association.

Method: Multiple regression analyses were conducted in a group of 404 older primary care patients assessed with validated measures.

Results: Bodily pain was independently associated with depression. Neuroticism moderated the associations between pain and both depressive symptom severity and major depression, albeit not independent of overall medical burden; the relationships were stronger in subjects with lower neuroticism scores.

Conclusions: The association of bodily pain with depression may be greater in those previously at lower risk on account of low neuroticism.

Key Words: Depression • geriatrics • personality • pain