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Am J Geriatr Psychiatry 14:334-342, April 2006
© 2006 American Association for Geriatric Psychiatry
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Article

Ethnicity, Stress, and Cortisol Function in Hispanic and Non-Hispanic White Women: A Preliminary Study of Family Dementia Caregivers and Noncaregivers

Dolores Gallagher-Thompson, Ph.D., A.B.P.P., Gia Robinson Shurgot, Ph.D., Kenneth Rider, Ph.D., Heather L. Gray, M.A., Christine L. McKibbin, Ph.D., Helena C. Kraemer, Ph.D., Sandra E. Sephton, Ph.D., and Larry W. Thompson, Ph.D.

From the Department of Psychiatry (DG-T, GRS, KR, HLG), Stanford University School of Medicine and VA Palo Alto Healthcare System; the University of California, San Diego (CLM) and VA Healthcare System; Stanford University School of Medicine (HCK); the University of Louisville School of Medicine (SES); and Pacific Graduate School of Psychology (LWT) and Stanford University School of Medicine.

Objective: This study examined differences in psychologic and physiological responses to caregiving stress in Hispanic and non-Hispanic white women dementia caregivers and noncaregivers. Dependent variables were perceived stress, depression, and salivary cortisol.

Method: Eighty-three women caregivers (20 Hispanic and 24 non-Hispanic white) and noncaregivers (19 Hispanic and 20 non-Hispanic white) completed the Perceived Stress Scale (PSS), Center for Epidemiological Studies-Depression Scale (CES-D), and collected three saliva samples daily for 3 consecutive days. A subsample of 17 Hispanic and 28 non-Hispanic white participants matched on age and education was used for the main analyses.

Results: Caregivers had higher levels of 8 am, 5 pm, and 9 pm log cortisol as well as higher perceived stress than noncaregivers. Non-Hispanic whites had higher depression scores than noncaregivers, but there was no significant difference for Hispanics. Hispanics, regardless of caregiving status had flatter daytime cortisol slopes than the non-Hispanic whites. Multivariate regression analyses showed that both ethnicity and depressive symptoms independently predicted daytime cortisol slope.

Conclusions: Results support the relationship between chronic stress and hypothalamic–pituitary–adrenal axis dysregulation among women dementia caregivers and highlight the need to examine further the role of ethnicity and depressive symptoms in their physiological responses.

Key Words: Ethnicity • stress • cortisol • dementia • caregiving




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