HOME HELP FEEDBACK SUBSCRIPTIONS ALL ISSUES SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kim, J.-M. Articles by Yoon, J.-S. Search for Related Content PubMed PubMed Citation Articles by Kim, J.-M. Articles by Yoon, J.-S.

A Prospective Study of Changes in Subjective Memory Complaints and Onset of Dementia in South Korea

From the Department of Psychiatry (JMK, SWK, SJY, ISS, JSY) and the Institute of Aging & Geriatrics (JMK, ISS, JSY), Chonnam National University Medical School, Kwangju, Republic of Korea; and King's College London (Institute of Psychiatry), London, United Kingdom (RS).

Objective: Subjective memory complaints (SMCs) are associated with an increased incidence of dementia, but changes in SMCs have received little investigation. This study aimed to investigate the prospective association between change in self-reported memory and incident dementia in a community sample.

Method: Korean residents aged 65+ without dementia were followed over a 2.4-year period (N = 686). SMCs were ascertained on both occasions using the Geriatric Mental State schedule. Incident dementia was ascertained at follow up, applying Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria.

Results: Compared with those without SMCs on either occasion, dementia incidence was higher in those with persistent SMCs (present on both occasions) and transient SMCs (present at baseline but not follow up). There was no association with new onset of SMCs during follow up. The association with transient SMCs was weakened when those with cognitive impairment at baseline were excluded.

Conclusions: Incident dementia is associated with memory complaints that persist or disappear but not with new complaints.

Key Words: Subjective memory complaints • dementia • cognitive function • depression

This article has been cited by other articles:

				R. Stewart, C. Dufouil, O. Godin, K. Ritchie, P. Maillard, N. Delcroix, F. Crivello, B. Mazoyer, and C. Tzourio Neuroimaging correlates of subjective memory deficits in a community population Neurology, April 29, 2008; 70(18): 1601 - 1607. [Abstract] [Full Text] [PDF]