AJGP
HOME HELP FEEDBACK SUBSCRIPTIONS ALL ISSUES SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Geriatr Psychiatry 13:808-814, September 2005
© 2005 American Association for Geriatric Psychiatry
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a Colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Morse, J. Q.
Right arrow Articles by Reynolds, C. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Morse, J. Q.
Right arrow Articles by Reynolds, C. F., III

Regular Article

Impact of Cluster C Personality Disorders on Outcomes of Acute and Maintenance Treatment in Late-Life Depression

Jennifer Q. Morse, Ph.D., Paul A. Pilkonis, Ph.D., Patricia R. Houck, M.S.H., Ellen Frank, Ph.D., and Charles F. Reynolds III, M.D.

Received February 25, 2004; revised June 23, August 19, 2004; accepted August 24, 2004. From Western Psychiatric Institute and Clinic, Pittsburgh, PA. Send correspondence and reprint requests to Dr. Morse, Personality Studies, Western Psychiatric Institute and Clinic, 3811 O’Hara St., Pittsburgh, PA 15213. e-mail: morsejq{at}upmc.edu
© 2005 American Association for Geriatric Psychiatry

Objective: Personality disorders (PDs) have been associated with poor treatment outcomes in acute treatments for late-life depression and with persistent functional impairment after recovery from an episode of depression. Methods: Using survival analysis and mixed-effects models, the authors examined the impact of Cluster C PDs on time-to-response and several aspects of functioning in acute and maintenance treatment of major depression in later life. Results: Cluster C PDs were associated with longer time-to-response during acute treatment and non-response in continuation or maintenance treatment. Although not statistically significant, there was evidence of a cumulative negative impact of Cluster C PDs and residual depressive symptoms on instrumental activities of daily living (IADLs) during maintenance treatment. Conclusions: These findings suggest that screening for PD may be important for clinicians treating late-life depression and that the combination of Cluster C PDs and residual depressive symptoms may predict functional declines even after recovery from the index episode of depression.

Key Words: Depression • Personality Disorders • Maintenance Treatment • Treatment Outcome






HOME HELP FEEDBACK SUBSCRIPTIONS ALL ISSUES SEARCH TABLE OF CONTENTS
Copyright © 2005 American Association for Geriatric Psychiatry