HOME HELP FEEDBACK SUBSCRIPTIONS ALL ISSUES SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bozikas, V. P. Articles by Bouras, C. Search for Related Content PubMed PubMed Citation Articles by Bozikas, V. P. Articles by Bouras, C.

Pathological Correlates of Poststroke Depression in Elderly Patients

Received December 2, 2003; revised May 4, June 10, 2004; accepted June 11, 2004. From the Department of Psychiatry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece (VPB, AK); Departments of Psychiatry (EK, CB, PG), and Rehabilitation and Geriatrics (GG, FRH), HUG Belle-Idée, University of Geneva School of Medicine, Geneva, Switzerland; Service of Old Age Psychiatry (PG), University of Lausanne School of Medicine, Lausanne, Switzerland. Send correspondence and reprint requests to Dr. Vasilis Bozikas, Department of Psychiatry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece, e-mail: vpbozikas{at}oneway.gr
© 2005 American Association for Geriatric Psychiatry

Objective: The authors examined the relationship between poststroke depression and location of stroke. Methods: They performed a clinicopathological analysis of 95 consecutively autopsied elderly initial-stroke survivors. Results: The severity of brain vessel arteriosclerosis and frequency of brain vascular lesions were not significantly different between 21 cases with poststroke depression and 74 cases without. Earlier death was the only variable significantly associated with poststroke depression. No lesion pattern characterized the depression group. Conclusions: Neuropathological data confirm that depression is associated with worse prognosis in elderly stroke patients and lend support to the hypothesis that psychological rather than neurological factors are the main determinants of poststroke depression.

Key Words: Depression • Stroke • Physical Comorbidity • Neuropathology

This article has been cited by other articles:

				R. G. Robinson Vascular Depression and Poststroke Depression: Where Do We Go From Here? Am J Geriatr Psychiatry, February 1, 2005; 13(2): 85 - 87. [Full Text] [PDF]