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Use of Cognitive Enhancement Medication in Persons With Alzheimer Disease Who Have a Family Caregiver

Results From the Resources for Enhancing Alzheimer's Caregiver Health (REACH) Project

Received April 17, 2003; revised June 13, 2003; accepted August 26, 2003. From the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA (SHB,SZ), the Department of Psychiatry, University of Miami School of Medicine, Miami, FL (SJC), the Department of Preventive Medicine, University of Tennessee, and Regional Medical Center, Memphis, TN (RB), and the Department of Psychiatry and University Center for Social and Urban Research, University of Pittsburgh, Pittsburgh PA (RS). Send correspondence to Steven Belle, PhD., Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 504 Parran Hall, 130 DeSoto St., Pittsburgh, PA 15261. e-mail: Belle{at}edc.gsph-pitt.edu
©2004 American Association for Geriatric Psychiatry

Objective: Aging populations show increased prevalence of cognitive impairment and dementia. Recent efficacy studies report on prescription medications and herbal preparations that affect cognitive functioning, but the prevalence and correlates of cognitive-enhancement (CE) medication use among community-dwelling older persons is not well studied. The authors examined the frequency and appropriateness of use, the importance of a family caregiver in medication decisions for dementia patients, and differences in access to medical care. Methods: REACH is a multisite feasibility study of several approaches to reducing the negative impacts of caregiving on those living with a family member with dementia. Data on medication use by care-recipients were collected at baseline and 1 year later. Results: At baseline, 31% of 1,222 care-recipients were using a CE medication. Factors independently related to CE use were age, education, functional status, and caregiver vigilance. Within 1 year, 14% started and 30% quit taking CE. Care-recipients more likely to be Starters had spouse-caregivers, more education, and fewer baseline ADL impairments. Quitters had more ADL deficits at baseline and became less able to perform ADL at follow-up than those who continued on CE. Conclusions: CE medication use among dementia patients with a family caregiver is relatively common, though there is substantial geographic variability. Our findings are mixed with respect to appropriate use of CE medications, suggesting areas for physician education. Our data indicate the importance of the caregiver in CE medication use and suggest that there may be disparities in access to healthcare among people with cognitive impairment.

Key Words: Dementias • Alzheimer Disease • Cognitive Enhancers • Cholinesterase Inhibitor

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				R. Schulz and T. L. Patterson Caregiving in Geriatric Psychiatry Am J Geriatr Psychiatry, June 1, 2004; 12(3): 234 - 237. [Full Text] [PDF]