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Am J Geriatr Psychiatry 1:82-84, February 1993
© 1993 American Association for Geriatric Psychiatry
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CLINICAL AND RESEARCH REPORT

Effects of Buspirone on Agitation Associated With Dementia

Kenneth M. Sakauye, M.D., Cameron J. Camp, PH.D., and Patricia A. Ford

Department of Geriatric Psychiatry, LSU Medical Center; the Woldenberg Center for Gerontological Studies, Touro Infirmary, New Orleans; and the Department of Psychology, University of New Orleans, Louisiana.

Ten patients with probable Alzheimer's disease participated in an open-label study of buspirone for agitation. The starting dose of 15 mg/day was increased by 5 mg every week until maximal improvement or 60 mg/day was reached. A significant decrease in agitation scores occurred at an average dose of 35 mg/day.




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